Requests

https://stackoverflow.com/questions/43938742/python-requests-upload-file

#!/usr/bin/env python3

import requests

url = 'https://EXAMPLE'

payload = {
  'one': 'EXAMPLE',
  'two': 'EXAMPLE',
  'three': 'EXAMPLE'
  }

files = {
  'doc': ('example.docx', open('/Path/to/example.docx', 'rb'), 'application/vnd.openxmlformats-officedocument.wordprocessingml.document')
  }

r = requests.post(url, data=payload, files=files)

print(r.json())